10
Dec 2025
Treatment with an immune and cancer cell-targeting antibody therapy eradicates residual traces of the blood cell cancer multiple myeloma, according to interim results from a clinical trial conducted by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.
10
Dec 2025
New psychoactive substances, originally developed as potential analgesics but abandoned due to adverse side effects, may still have pharmaceutical value if researchers could nail down the causes of those side effects.
10
Dec 2025
Dietary restriction reshapes CD8+ T cell metabolism by increasing ketone body–driven acetyl-CoA production, preventing terminal exhaustion and enhancing tumour control in mice. This metabolic reprogramming also boosts responsiveness to PD-1 blockade, suggesting a potential strategy to improve cancer immunotherapy.
10
Dec 2025
The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types that plays a key role in this protection is the microfold cell, or M cell.
10
Dec 2025
Offering screening for neurodivergence to people detained by the police could help ensure access to appropriate support and fairer treatment in the criminal justice system, say Cambridge researchers, after a study suggests that one in two individuals arrested and detained in London may have undiagnosed attention-deficit/hyperactivity disorder (ADHD) and one in 20 may have undiagnosed autism.
10
Dec 2025
Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to mitigate tissue and organ damage associated with heart attacks, strokes and traumatic injuries.
10
Dec 2025
This comprehensive review examines vitamin B12 absorption, physiological roles, deficiency states, and dietary sources, with particular attention to differences between natural and synthetic forms. The authors conclude that while all B12 forms raise circulating levels, methylcobalamin may offer advantages in specific clinical contexts, especially where absorption or metabolic conversion is impaired.
10
Dec 2025
Synaptic plasticity — the brain's ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.
10
Dec 2025
For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but a group of leading microbiologists think they may have cracked the case.
10
Dec 2025
As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.
Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
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