9
Dec 2025
A test using genetics to predict who is at the highest risk of developing type 1 diabetes could one day be applied to largescale health studies, to identify adults who could benefit from new drugs, new research shows.
9
Dec 2025
At any one time, nearly 1 in 5 emergency department patients in the UK is being cared for in corridors, waiting rooms, and other non-standard 'overflow' spaces-an approach known as escalation area care-suggest the results of a large observational study, published online in Emergency Medicine Journal.
9
Dec 2025
A new report warns Deaf women experiencing domestic abuse in Scotland remain "effectively invisible" due to the chronic absence of specialist services and a lack of coordinated national support.
9
Dec 2025
University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.
9
Dec 2025
Doctors treating seriously ill patients in an emergency setting may want to give the sedative etomidate, rather than ketamine, while placing a breathing tube, according to a randomized trial published in the New England Journal of Medicine.
9
Dec 2025
Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce metabolic inflammation and improve glycaemic control in high-fat-diet-fed mice. Choline-driven increases in TMA production replicated these benefits, revealing a host–microbe signaling axis with therapeutic potential for obesity-associated insulin resistance.
9
Dec 2025
Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce metabolic inflammation and improve glycaemic control in high-fat-diet-fed mice. Choline-driven increases in TMA production replicated these benefits, revealing a host–microbe signaling axis with therapeutic potential for obesity-associated insulin resistance.
9
Dec 2025
Mpox virus clade Ib shows a longer and more variable incubation period than previously characterized clades, with symptom onset extending well beyond 21 days in a substantial minority of cases. Incubation varies by transmission route, with shorter intervals after sexual exposure and longer periods following nonsexual community transmission, raising implications for surveillance and postexposure guidance.
9
Dec 2025
A large volcanic eruption or cluster of eruptions in the mid-1340s triggered severe climate anomalies that drove harvest failures across parts of Europe. These shocks reshaped Mediterranean grain trade routes, likely introducing plague-infected fleas into Italian ports and helping ignite the Black Death.
9
Dec 2025
Nancy Hunt arrived at an emergency room from a Genesis HealthCare nursing home in Pennsylvania in such dreadful shape, including maggots infesting her gangrened foot, that the hospital called an elder abuse hotline and then the police, her son alleged in a lawsuit.
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